Columbia University

Technology Ventures

Autistic spectrum, gastrointestinal disorders, visceral inflammation, central nervous system disorders, autoimmune disorders treatment

Technology #1534

“Name of the inventors: Martha Welch M.D., David Ruggiero Ph.D., Muhammad Anwar

Gut and brain disorders treatment for Autism, gastrointestinal disorders, visceral inflammation, central nervous system disorders Description: Novel multipeptide regimens and associated kits comprising a combination of secretin and oxytocin for use in treating and/or preventing gastrointestinal disorders, central nervous system disorders, autoimmune diseases and pain are described.

The pharmaceutical compositions described contain one or more protease inhibitors in addition to a therapeutically effective combination comprising secretin and oxytocin.

Peptide therapy, particularly those utilizing co-administration of secretin and oxytocin, provides a simultaneous resolution of gut and brain disorders. Gut and brain areas affected by co-administration of secretin and oxytocin overlap those affected in autism. ”